Bianconi sueceeded his teacher Camillo Ranzani as professor of Natural History at the University of Bologna.

[1][2] In 1874, Bianconi published a book on "independent creations", which utilized zoological arguments against Darwinism.

The book sold well and Bianconi and his son Giovanni Antonio published a revised Italian edition in 1875.

[3] Bianconi argued that "enlightened application of laws of mechanics, physics, physiology" led to the conclusion that every part of an organism had been created by the "unlimited intelligence" of God.

[4] He published numerous papers, in both Italian and Latin, in the journal Novi Commentarii Academiae Scientiarum Instituti Bononiensis (beginning in 1844) and its successor Memorie della Accademia delle Scienze dell'Istituto di Bologna (from 1850 onward).