Brescianello's name is mentioned for the first time in a document from 1715 by which Maximilian II Emanuel, Elector of Bavaria conferred on him an appointment as violinist in the court orchestra in Munich.
Soon after, in 1716, following the death of Johann Christoph Pez, Brescianello was given a post at the court in Stuttgart of Eberhard Ludwig, Duke of Württemberg, as director of music and maître des concerts de la chambre.
Around 1718, he composed the pastorale opera La Tisbe, which he dedicated to the Archduke in the vain hope that it would be listed at the Stuttgart theatre.
In the years from 1719 to 1721 there arose a fierce conflict when Reinhard Keiser launched repeated attempts to obtain Brescianello's post.
In 1744, the court's financial situation improved and Brescianello was reappointed Oberkapellmeister by Duke Karl Eugen, in consideration of "his special knowledge of music and excellent skills".