[1] Born in Bagheria, in the province of Palermo, he became the regent of Brancaccio's mandamento after the arrest and subsequent incarceration of the Mafia boss Gaspare Spatuzza in 1998.

“To initiate the process of remodeling the image of Cosa Nostra,” Giuffrè explained, “Guttadauro made contacts in business and started a debate on how best to apply peacefully the process of silent reconstruction of Cosa Nostra.”[2] Guttadauro’s grand Palermo villa served as a meeting point for both mafiosi and the people that counted in public life.

According to prosecutor Roberto Scarpinato: “… first of all members of the military Mafia would come to receive instructions regarding protection rackets, drug trafficking, and other crimes.

[4][5] Police had bugged Guttadauro’s apartment and he was overheard discussing political appointments with the city's public health councillor Domenico Miceli, himself a doctor.

[9] On October 15, 2007, the prosecution requested eight years' imprisonment for Cuffaro for passing confidential information to the so-called moles in the Palermo Antimafia directorate.