[3] He was consecrated on 26 May 2007 by Enrico Masseroni, Archbishop of Vercelli, and Bishops Fernando Charrier and Natalino Pescarolo as co-consecrators.

After four years as Bishop of Alessandria, on 21 September 2011, Pope Benedict XVI named Versaldi President of the Prefecture for the Economic Affairs of the Holy See and gave him the rank of archbishop.

[4] On 18 February 2012 he was created Cardinal-Deacon of Sacro Cuore di Gesù a Castro Pretorio by Benedict XVI.

[7] On 31 March 2015 Pope Francis appointed him Prefect of the Congregation for Catholic Education, replacing Cardinal Zenon Grocholewski.

The agreement widened the variety of academic titles recognized for the teaching of Roman Catholic religion in the Italian public primary and secondary schools.