[1] Since 1926 Glakho Zakaryan was soloist of the Georgian Philharmonic.
He performed the songs of Armenian ashiks, mainly Sayat-Nova (Zakaryan's performance of the song "Dun en glkhen imastoun iss..." ("You are wise since then") is heard in the Armenian TV movie "Sayat-Nova", 1960).
[2] In 1934, as part of the "Mountain Eagles" joint multinational ensemble, he performed on tour in many cities of the USSR.
In 1939, he participated in the ten-day exhibition of Georgian art and literature in Moscow, in 1943–1945, he led the group of duduk players in the Georgian Song-Dance Ensemble.
He gave concerts in Yerevan, Moscow, Leningrad, Vladivostok, and Central Asian cities.