The Glenn–Fowler expedition to Santa Fe, New Mexico was led by Hugh Glenn and Jacob Fowler to see whether trade with the Spanish in the region would be feasible.
[a] They left their establishment on the Verdigris River in present-day Oklahoma on September 25, 1821, and arrived in Santa Fe in January 1822, and found that the Spanish authority in the region had been ended by the Mexican War of Independence.
[3] Colonel Hugh Glenn was formerly an Ohio banker and businessman who came to the Indian Territory, where he opened a trading post near the mouth of the Verdigris River.
They began to encounter Kiowas in large numbers during the following week, but the meetings were tense and establishing trade was nearly impossible.
Moving on, the party met Spanish troops in Taos who informed them that the area now belonged to Mexico, which had defeated Spain in the Mexican Revolution.
It not only met the original objective of proving feasibility of trade between the United States and Spanish North America, but confirmed the route that would later be followed by the Santa Fe Trail.