The order includes saprobes, endophytes and pathogens on plants, animals and other fungi with representatives found all over the world in varying habitats.

The asci are unitunicate, 8-spored and inamyloid, and the apex is either thickened without visible discharge mechanism or thin-walled with a distinct annulus.

[1] Families Reticulascaceae and Malaysiascaceae are typically involved in nutrient cycling as saprobes on decaying plant matter.

In 2015 and 2016, the previously described Incertae sedis Sordariomycetes group Plectosphaerellales was placed in Glomerellales based on molecular data phylogenetic analyses.

Hyde later described a new family Malaysiascaceae (2018) to accommodate the previously described Incertae sedis Glomerellales genus Malaysiasca (Crous & M.J.