Gmina Prusice is an urban-rural gmina (administrative district) in Trzebnica County, Lower Silesian Voivodeship, in south-western Poland.

Its seat is the town of Prusice, which lies approximately 11 kilometres (7 mi) north-west of Trzebnica, and 28 kilometres (17 mi) north of the regional capital Wrocław.

The gmina covers an area of 158.02 square kilometres (61.0 sq mi), and as of 2019 its total population is 9,374.

Apart from the town of Prusice, the gmina contains the villages of Borów, Borówek, Brzeźno, Budzicz, Chodlewko, Dębnica, Gola, Górowo, Jagoszyce, Kaszyce Wielkie, Kopaszyn, Kosinowo, Krościna Mała, Krościna Wielka, Ligota Strupińska, Ligotka, Pawłów Trzebnicki, Pększyn, Pietrowice Małe, Piotrkowice, Raszowice, Skokowa, Strupina, Świerzów, Wilkowa and Wszemirów.

This Trzebnica County location article is a stub.