It is an obligate biotroph that infects plants in several families including Acanthaceae, Asteraceae,[1] Brassicaceae,[2] Cucurbitaceae,[3] and Lamiaceae.

Causes powdery mildew disease in multiple families including Acanthaceae, Asteraceae, Brassicaceae, Cucurbitaceae, etc.

Conidia are dispersed through the wind, water droplets, and similar methods to nearby plants to start new infections.

The control of Golovinomyces orontii and powdery mildew diseases generally involves a combination of chemical and nonchemical strategies.

For many vegetable crops, sulfur, copper-based products, chlorothalonil, horticultural oil, potassium bicarbonate, and Bacillus subtilis can be used for powdery mildew control.