Major regional centres of the Goulburn Valley are Shepparton, Seymour, Echuca, Benalla, Yarrawonga and Kyabram.
European Settlement In 1824, Hume and Hovell on their return from Port Phillip, camped by the Goulburn River not far upstream of Seymour.
Industries in the Goulburn Valley include agricultural activities such as fruit growing and dairying, which supply processing plants in Shepparton and outlying towns such as Strathmerton and Tongala.
[9] Local government in the region is provided by the City of Greater Shepparton and the Shires of Mitchell, Moira, Campaspe, Murrindindi, and Strathbogie.
At the state level, the region includes the Electoral districts of Shepparton, Murray Plains, Euroa and Eildon.
Passenger rail services are provided from Melbourne to Seymour railway station the junction for they North East and Goulburn Valley lines which was opened in 1872 and then onto Shepparton and Echuca by V/Line.