In 2006, Government of Uttar Pradesh decided to set up a new medical college and hospital at Azamgarh in the eastern part of the state at an approximate cost of ₹300 crore (equivalent to ₹964 crore or US$110 million in 2023).

seats by Medical Council of India (now National Medical Commission)[citation needed] In 2006, OPDs were started which gradually shifted to 140 Bedded IPD & Presently GMC & SFH is running with 550 Beds IPDs, well created emergency & Private wards.

The Academic activities started in August 2013 with first Batch of MBBS students.

The Government Medical College & Super Facility Hospital is situated at Chakrapanpur of the historic city of Azamgarh in U.P.

GMC & SFH is spread in 105 acre area which includes Administrative Block, Academic Block, Central Library, Examination hall, Auditorium, Lecture Theater & Various Departments of Medical Education.