She was among the 10 women who were elected unopposed on 27 June 1960 on the ticket Convention People's Party.
[13] Ayensu volunteered for several organizations including serving as first woman President for the Sekondi/Takoradi Consumers' Cooperative Society in 1945 and patron of the Sekondi/Takoradi branch of the National Youth League in the early 1950s.
[11][15] That same year, she received a certificate of honour and a badge from the Department of Social Welfare for her voluntary services in Sekondi/Takoradi Municipality.
[17][18] She served on the Board of Governors of Sekondi College and Fijai Day Secondary School.
Grace Ayensu was married to an administrator who worked with the Ghana railways.