[3] In May 1894 she married her fellow medical graduate, German-born Paul Wilhelm Rudolph Boelke.
[2] She was a convenor of the National Council of Women of New South Wales' health committee during 1913–26, a vice president of Sydney's Town Planning Association, and a founding member of New South Wales branch of the League of Nations Union in 1921.
She was employed by Berlei, an Australian lingerie manufacturer, from 1923 to 1926 as a medical director, a role that involved overseeing the welfare of the company's female workers and ensuring the "correct anatomical lines of their garments".
Grace Boelke spent her later life travelling overseas for research into women and children's health, and moved to the suburb of Leura in the Blue Mountains.
She died in Manly, New South Wales on 17 February 1948, leaving her estate to the British Royal Society of Medicine for the funding of medical research.