Grambling State is home of the Eddie G. Robinson Museum and is listed on the Louisiana African American Heritage Trail.

Grambling State University developed from the desire of African-American farmers in rural north Louisiana who wanted to educate other African Americans.

In 1896, the North Louisiana Colored Agriculture Relief Association led by Lafayette Richmond was formed to organize and operate a school.

After opening a small school west of what is now the town of Grambling, the Association requested assistance from Booker T. Washington of Tuskegee Institute in Alabama.

The Grambling science building is one of twenty-six public structures in Louisiana constructed by the prominent contractor George A.

[18] In 2020, Grambling State University became the first collegiate institution in Louisiana to offer bachelor's degrees in cybersecurity and cloud computing.

As of 2022[update], approximately 40% of GSU's student body is from outside Louisiana; Texas, California, and Illinois are the three largest feeder states.

[22] Alumni of Grambling State include numerous MLB, NBA and NFL players, public officials, lawyers, doctors, scholars, journalists, business professionals, and artists.