The bridge was officially named after Grand Duchess Charlotte of Luxembourg during ceremony for the arrival of the first section of the support structure on 20 June 1963.

Since 28 July 2018, the bridge also forms part of the City Tram Line 1, operated by LuxTram, utilising rails installed in the surface of the deck during renovation works carried out from 2015 to 2018.

[3] In 1952, following a failure between the partner countries to agree on a permanent location, Luxembourg became the temporary seat of the institutions of the newly created European Coal and Steel Community (ECSC).

The components of the twin box girders forming the structure of the bridge were first assembled in Germany, before being transported, in 3 m by 13 m segments, to the site by train and then by road.

The bridge was subjected to overload tests involving the simultaneous passage of twelve M48 Patton tanks, of 42 tons each, made available by the Belgian army.

Significant alterations and renovations to the bridge took place between 2015 and 2018, costing approximately 40 million euros, as part of plans to reintroduce trams to Luxembourg City's transport infrastructure.

The road deck sits 75 meters above the Alzette River and is composed of an orthotropic slab of steel supported by two parallel box girders, each 6 m wide.

The distinctive red paint coat of the box girder structure results from a deliberate decision by the designers to make the bridge noticeable, even in foggy or obscure conditions.

In 2016, for the fiftieth anniversary of the bridge, a postage stamp made by the German artist, Anita Wünschmann, and a 2 euro commemorative coin were issued.