Grandidier's tufted-tailed rat (Eliurus grandidieri) is a species of rodent from the family Nesomyidae.

[2] Grandidier's tufted-tailed rat is present in sclerophyllous forest and is presumed to be a partly scansorial species.

[1] Female Grandidier's tufted-tailed rats are believed to give birth to up to three young.

[1] There is sufficient evidence that all species from the family Nesomyidae, especially those that commonly live upwards of 800 m (2,600 ft), are susceptible to a 100 percent mortality rate from plagues carried by introduced rodents, and these seem to be localized events.

[1] The species is located in three protected areas: the Anjanaharibe-Sud and Manongarivo Special Reserves and the Marojejy National Park.