Grayson Valley is an unincorporated community and census-designated place in the northeastern Birmingham area, in Jefferson County, Alabama, United States.

It is located between the Spring Lake neighborhood of Birmingham, Alabama and the Birmingham suburbs of Clay, Trussville, and Center Point.

[citation needed] At the 2020 census, the population was 5,982.

As of the 2020 United States census, there were 5,982 people, 2,598 households, and 1,718 families residing in the CDP.