It was released in the United Kingdom on 28 November 2011 by Island Records.

It includes fourteen of the group's singles, (excluding "Feva Las Vegas" and "We Dance On"), one album track, two live lounge covers and the original N-Dubz version of Dappy's first solo single, "No Regrets".

[1] The album's release comes after the group announced an indefinite hiatus to focus on solo careers.

[2] Following the announcement of their Reformation Tour in May 2022, the album saw a resurgence in popularity, surpassing the peak of 38 upon the album's original release, entering the top 10 at number 10 on 27 May 2022.

Jon O'Brien From AllMusic gave the album a mixed review and felt that their "Greatest Hits feels like a cynical cash-in that's appeared way too early in the band's career to make any impact.