Greco Island is part of the larger Don Edwards San Francisco Bay National Wildlife Refuge.

[3] San Mateo County plans from 1969 called for continued development of the Port of Redwood City area with recreational facilities by acquiring the land on Greco Island.

[4] Greco Island was one of the first areas along with Fremont, Mowry Slough, and Alviso to be included in a proposal for The San Francsico Bay National Wildlife Refuge in 1972.

[5] In 2007 a report on the shoreline of the island determined that it was composed of fine sediment forming extensive mudflats that are submerged during high tide.

In more recent years concerns over sea level rising have encouraged more active recovery of marshland in the bay including the areas surrounding the island.