At the time of construction, it was serviced by steam engines inbound and outbound from the Melbourne CBD, until the completion of the electrification from Heidelberg to Eltham in 1923.

In the late 1960s and early 1970s, the station was upgraded to two tracks, and a single offset island platform was built.

[10] In May 2019, the Victorian State Government announced a plan to duplicate the line between Greensborough and Eltham, which included an upgrading of the station.

[1] Until 2023, the timetabling for services to and from the station remained practically the same, due to the single-track railway between Greensborough and Hurstbridge, with only crossing loops located at Eltham and Diamond Creek.

[13] Platform 1: Platform 2: Dysons operates five bus routes via Greensborough station, under contract to Public Transport Victoria: Kinetic Melbourne operates three routes via Greensborough station, under contract to Public Transport Victoria: Panorama Coaches operates one route to and from Greensborough station, under contract to Public Transport Victoria: