[4] The Greenville franchise joined the Baton Rouge Cajuns, Natchez Indians and Vicksburg Hill Climbers teams as charter members in the newly formed league.
[1][5][6] The league schedule began on May 8, 1902, and Greenville opened at home on that date against Baton Rouge.
[10][11] In their first season of play the 1902 Greenville Cotton Pickers finished last in the four-team league in a close race between the four teams.
The manager was Bell Hebron as Greenville finished 3.0 games behind the first place Natchez Indians in the final standings.
[13] John Lawrence Hebron Jr., nicknamed "Bell" was a Greenville native who was a local attorney.
[27] The Grays had a 53–64 record under manager Billy Smith and finished 21.5 games behind the first place Baton Rouge Red Sticks in the final standings.
[28][29][12] Greenville player/manager Billy Smith won the Cotton States League batting title, hitting .308.
[30][31] In 1903, Rothermel had played in the league Cotton States for the Baton Rouge Red Sticks.
The Cotton Pickers ended the season 20.0 games behind the first place Pine Bluff Lumbermen.
[35] Blackwell pitched for the Cotton Pickers in 1904 at age 34 and compiled an 18–12 record in 30 games for Greenville.
[36] Blackburn ended his 15-season professional career in the Cotton States League 1908 with the Vicksburg Hill Climbers.
[12] Greenville was led by manager George Reed and placed first in league standings in the shortened season.
The Cotton Pickers had a record of 50–25 as Greenville finished 5.5 games ahead of the second place Meridian White Ribbons in the standings.
[38][39][12] Greenville player Mike Welday won the Cotton States League batting title, hitting .349 in the shortened season.
[43][30] He served as the player-manager of the Denver Bears in 1916 and 1917 and later attempted to purchase the Pittsburgh Pirates, which proved unsuccessful.
[48] He also pursued purchasing the Boston Braves, Philadelphia Phillies and St. Louis Cardinals and was unsuccessful in each instance.