Born in Juiz de Fora, Minas Gerais, Gregore was a Joseense youth graduate.
[8] On 11 May 2016 he made his professional debut, coming on as a second-half substitute for Fernando Medeiros in a 3–0 away win against Galvez, for the year's Copa do Brasil.
[13] On 20 August, Bahia bought more 40% of Gregore's economic rights, in order to own 90% in total, with his contract expiring at the final of the 2021 season.
[16] On 11 March 2023 in a game against New York City FC, Gregore suffered a Lisfranc injury and was ruled out for six months.
[19] On 19 February 2024, Inter Miami CF announced that it had transferred midfielder Gregore to Brazilian Serie A side Botafogo.