Gregorio Petrocchini (1535 – 19 May 1612) was an Italian cardinal at the end of sixteenth and early seventeenth century.
Gregorio Petrocchini was born in 1535 in Montelparo, now in the province of Fermo in the region of Marche, then in the Papal States.
In response to general expectations, Pope Sixtus V appointed Petrocchini superior general of his order in a ceremony in Rome in 1587, after the death of P. Spirito Vicentini.
At the end of 1588 the Pope named him Apostolic Commissioner to visit the monasteries of his order in Spain.
Cardinal Petrocchini died in Rome on 19 May 1612 at the age of 77 years.