Born in Malines, De Reyghere studied voice at the Brussels Conservatory, where she received diplomas in concert singing, opera and art song.
[2] She has collaborated in the 1980s and 1990s with the ensemble Ricercar Consort conducted by Philippe Pierlot, performing choral music with one voice per part.
106, a church cantata for soprano, women's choir and small orchestra, by the Bruges composer Joseph Ryelandt, with Ignace Michiels at the organ.
[5] In 2000 they recorded Bach's four short masses, with Wilke te Brummelstroete, James Gilchrist and Jan van der Crabben.
[7] A reviewer of a recording of motets and psalm settings by Felix Mendelssohn noted her "under-statement and beauty of line and texture".