He was the founder of the "Greek-speaking Hotel" (Hellenoglosso Xenodocheio or Ελληνόγλωσσο Ξενοδοχείο), a secret organization established in Paris in 1809 to assist Greeks against Ottoman rule.
He attended school in his hometown and then went to Bucharest to study with the academic Lampros Fotiadis.
He settled there and became Marie-Gabriel-Florent-Auguste de Choiseul-Gouffier's secretary, helping him to publish his book Voyage pittoresque en Grèce.
Zalykis was the founder of the "Greek-speaking Hotel", Hellenoglosso Xenodocheio, a secret organization established in 1809.
Zalykis went to Saint Petersburg, where he met emperor Alexander I of Russia and took important financial help.