Accumoli is a comune (municipality) in the Province of Rieti in the Italian region of Lazio, located about 110 kilometres (68 mi) northeast of Rome and about 45 kilometres (28 mi) northeast of Rieti.

Located at an altitude of 855 m above sea level in the Umbria-Marche Apennines, Accumoli is an enclave within the province of Ascoli Piceno.

The climate is typical internal Apennines with cold, snowy winters and summers almost never too hot.

The town has its origins in the 12th century, when the territory in the Valle del Tronto was ruled by the Normans and later the Kingdom of Naples.

On 24 August 2016, numerous buildings were destroyed and damaged by the Central Italy earthquake.