Although it is classified as a "joint use" facility, Grosseto Airport is primarily an Italian Air Force (Aeronautica Militare) Base, home of the 4th Stormo, equipped with the Eurofighter Typhoon.

However, the facility is used as a commercial airport by civilian charter flights and private aircraft.

Later, the 57th Fighter Group, used the airfield from 24 September 1944 to 29 April 1945, and later between 7 May and 15 July 1945, also flying combat operations with P-47s.

[3][4] The 47th Bomb Group, and its four squadrons, the 84th, 85th, 86th, and 97th, using A-20 and A-26 Attack aircraft also used the airfield, mostly flying night intruder missions, from 11 December 1944 to 23 June 1945.

[5] In the fifties, expansion and modernization works were carried out on the entire airport infrastructure, which then led to the resumption of military activities and the inauguration of the first civil flights: always in that period, starting from 1959 the airport became the final seat of the 4th Wing (aerobrigata founded in 1931 at the Udine-Campoformido airport), while on 1 June 1961 the 9th Fighter Group of Italian Air Force.