The Grote Kerk or Onze-Lieve-Vrouwekerk (Church of Our Lady) is the most important monument and a landmark of Breda.

After being displaced several times, the organ arrived at its present location in the church in 1712.

The Prinsenkapel (Prince chapel) north of the choir is the old mausoleum of the van Nassau-Breda dynasty, ancestors of the Dutch royal family, the House of Orange-Nassau.

[2] The chapel was built from 1520 until 1525 on orders of the Lord of Breda, Henry III of Nassau-Breda.

Among them; William the Silent intended to be buried in the chapel, but Breda was at that time occupied by the Spanish.

The frescos are made by the Italian painter Tommaso di Andrea Vincidor (a student of Raphael).