[1] George Gruhn began collecting and selling vintage American guitars while attending college, eventually establishing himself in the folk festival circuit.
[2][3] On January 2, 1970, Gruhn opened the business with an inventory of 22 instruments in a 20 x 40 foot space at 111 4th Avenue North,[4] in what was then a rundown section of downtown Nashville's Lower Broadway district, next to the stage door of the Ryman Auditorium, the home of the Grand Ole Opry.
The store was originally named GTR, which stood for George Gruhn, business partner Tut Taylor and employee Randy Wood.
The store became known as a mecca for professional musicians and well-heeled collectors of vintage musical instruments, including such notable artists as Duane Allman, Mark Knopfler, Robert Plant, Sturgill Simpson, Joe Bonamassa, Eric Clapton, Billy Gibbons, and Rick Nielsen.
[5] On December 31, 2006, Garrison Keillor visited Gruhn Guitars with Vince Gill for his New Year's Show at Ryman Auditorium for PBS' Great Performances.