The country made its début at the 1976 Summer Paralympics in Toronto, with a delegation of eleven athletes to compete in archery, dartchery, swimming, table tennis and weightlifting.
It sent a single weightlifter to the 1988 Games, then was absent for sixteen years, before returning for the 2004 Paralympics, represented by two runners.
Weightlifter J.R. de Leon won his country's only medal during its inaugural participation in 1976, lifting 150 kg in the men's featherweight category, to take bronze.
Guatemala's first (and so far only) gold medal also came in weightlifting, and was won by José Rolando, the only Guatemalan representative at the 1988 Games.
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