Guiding County (simplified Chinese: 贵定县; traditional Chinese: 貴定縣; pinyin: Guìdìng Xiàn) is a county of south-central Guizhou, China.

It is under the administration of the Qiannan Buyei and Miao Autonomous Prefecture.

The county seat is located in the town of Chengguan.

The town of Changmingzhen (昌明镇) has a Laoganma factory that opened during the COVID-19 pandemic in China.

[1] Guiding County is divided into 2 subdistricts and 6 towns:[2]