During the Yuan dynasty, it was reorganized as the Zhenyuan Military and Civilian Prefecture, with the annexed Anyi County.

In the early Ming dynasty, Zhenyuan was established as a prefecture and a military garrison.

During the Yongle era, it was upgraded to Zhenyuan Prefecture, with all administrative units located within the same city.

In 1956, the Qiandongnan Miao and Dong Autonomous Prefecture was established, initially with Zhenyuan as its capital, before relocating to Kaili in 1958.

The local people mainly believe in Chinese folk religion, Taoism, Buddhism and Catholicism.

[4] Agriculture is an important part of Zhenyuan County's economy, of which rice farming and vegetable cultivation represent the largest sector.

[4] In addition, tourism (particularly related to history and wine) is a significant and growing portion of the economy.

Throughout history, Zhenyuan has been visited or guarded by numerous literati, military generals, including renowned figures such as Zhang Sanfeng, Wang Shouren, Wu Sangui, Wu Jingzi, Lin Zexu, Li Liejun, Feng Yuxiang, and others.