Guillermo Owen (born 1938) is a Colombian mathematician, and professor of applied mathematics at the Naval Postgraduate School in Monterey, California, known for his work in game theory.

He is currently holding the position of Distinguished Professor of applied mathematics at the Naval Postgraduate School in Monterey, California.

Owen was named Honorary President of the XIV Latin Ibero American Congress on Operations Research - CLAIO 2008.

The university of Lower Normandy, in Caen, France, gave him an honorary doctorate in October 2017.

Owen has authored, translated and/or edited thirteen books, and approximately one hundred and forty papers published in journals such as Management Science, Operations Research, International Journal of Game Theory [de], American Political Science Review, and Mathematical Programming, among others.