Guizhou or Gui Prefecture (媯州) was a zhou (prefecture) in imperial China, centering on modern Zhangjiakou, Hebei, China.
It was created in 634 by the Tang dynasty and was later ceded by Later Jin to the Khitan-ruled Liao dynasty as one of the Sixteen Prefectures.
The administrative region of Guizhou in the Tang dynasty is in modern Zhangjiakou in northwestern Hebei.
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