Van Cortlandt Park and the Mosholu Golf Course are both located at the western terminus of Gun Hill Road.

After an intersection with Jerome Avenue, Gun Hill Road passes to the south of the Mosholu Golf Course.

[1] At an intersection with DeKalb Avenue in Norwood, the road passes by North Central Bronx Hospital and Montefiore Medical Center.

At Webster Avenue, Gun Hill Road passes the Williams Bridge station of the Metro-North Railroad.

[3] In the mid-1960s, the Tri-State Transportation Commission proposed a new route just a mile north of Gun Hill Road called the City Line Expressway; this plan also did not advance.