Guo Kexin (Chinese: 郭可信; 1923–2006), also known as Ke-Xin Guo or K. H. Kuo (Ke-Hsin Kuo), was a Chinese chemical engineer, physicist, metallurgist and crystallographer.

He was an academician of the Chinese Academy of Sciences, and is a pioneer of electron microscopy in China.

[citation needed] Guo was the Director and a senior researcher at the Beijing Electron Microscope Open Laboratory (a.k.a.

[1] Guo was the main founder of the Chinese Society for Electron Microscopy (a.k.a.

Chinese Electron Microscopy Society, CEMS; 中国电子显微镜会), and served as its Director/President from 1982 to 1996.