Gustavo Cuervo Rubio (6 December 1890 – 3 April 1978) [citation needed] was a Cuban doctor and politician.

He was an unsuccessful candidate for vice president in the election of 1936.

He was the Foreign Minister of Cuba during the presidency of Ramón Grau in 1944–1948.

They had one child: Gustavo Cuervo (Rubio) Jr.

He is the Grandfather of Gustavo Cuervo Rubio 3rd.