Gustavo Palafox (15 November 1923 – 21 August 2006) was a Mexican tennis player.

[1] Palafox won five Pan American Games gold medals during the 1950s.

[2] He competed at the US National Championships four times and made the third round in 1952, with wins over Robert Kerdasha and Don Eisenberg, before a loss to 11th seed Gardnar Mulloy.

In Davis Cup tennis, Palafox took part in nine ties and 20 rubbers, for 10 wins.

[3] He beat Australian Ken McGregor in 1950 and four years later made history when he beat Vic Seixas, becoming the first Mexican to defeat an American in the Davis Cup.