After the 2001 season, Pnini began his professional career, by playing with Maccabi Ra'anana in the Israeli Super League.

At the 2005 Maccabiah Games, Pnini was named tournament MVP as Team Israel won a gold medal in men's basketball.

Hapoel Jerusalem appealed against the agreement to the IBA court, claiming that it was an unsportsmanlike situation that their player had a signed contract with their league opponents.

In December 2012, he was fined NIS 100,000, stripped of his role as the team's captain, and suspended, as the result of a Nazi slur that he used against another player, during a game.

[7] On April 4, 2019, Pnini was named Israeli Player of the Month after averaging 12.4 points and 5.2 assists, shooting 46 percent from three-point range in four games played in March.