Williams' trauma from the death prompted him to leave Chicago and transfer to the Henry Ford Academy School for Creative Studies in Detroit, Michigan, where his uncle and Lewis' brother was the principal.

[3] As a junior, Williams averaged 22 points and 25 rebounds per game for Henry Ford Academy, registering five triple-doubles, and was named Michigan Metro Athletic Conference Player of the Year.

[1] While recovering from the injury, he played limited minutes for The Family at the Nike Elite Youth Basketball League.

[4] As a senior, Williams averaged 20 points and 21 rebounds per game, leading his team to the district title.

Williams struggled to control his weight in high school, weighing up to 320 lbs (145 kg) in his final year.

He committed to play college basketball for Purdue on July 6, 2017, over offers from Michigan State, Illinois and Xavier, among others.

On July 11, 2024, Williams signed a two-year deal with Alba Berlin of the German Basketball Bundesliga.

[25] On December 22, 2024, Williams signed a one-and-a-half-year contract with Maccabi Tel Aviv of the Israeli Basketball Premier League and the EuroLeague.

[26] Williams played for the United States at the 2019 FIBA Under-19 Basketball World Cup in Heraklion, Greece.