[4][5] He is the cousin of Peter Berg, who directed the film adaptation of Bissinger's book Friday Night Lights.

Bissinger's article for Vanity Fair, "Gone with the Wind" (August 2007), about the saga of 2006 Kentucky Derby Winner Barbaro, has been optioned by Universal Pictures.

[9] Bissinger wrote a piece in August 2020 saying that he and his wife would move to Italy if Donald Trump were re-elected President of the United States.

A Prayer for the City, published in 1998, offers insight into the urban political scene of Philadelphia during Mayor (who later became the Governor of Pennsylvania until 2011) Ed Rendell's term in the 1990s.

As part of the promotion of Shooting Stars, Bissinger appeared as a "Guest Commenter" on a Deadspin post on October 1, 2009.

Father's Day, published in May 2012 by Houghton Mifflin Harcourt, is a memoir that revolves around a singular cross-country road trip taken with one of his twin sons, Zach, an autistic savant.

In 2022 Bissinger wrote The Mosquito Bowl: A Game of Life and Death in World War II, which was widely reviewed.

[22] In a column published in GQ, Bissinger states he is a shopaholic with an obsession for expensive designer clothes, spending $638,412.97 between 2010 and 2012.