The division releases between 10 and 15 documentaries per year for the network and provides limited theatrical distribution of certain films prior to their initial broadcast on HBO's linear television and streaming services.

Also in 2006, documentary artist Lauren Greenfield directed Thin, a feature-length film about four young women struggling with eating disorders seeking treatment at the Renfrew Clinic in Florida.

[11] In November 2012, HBO aired the four-part documentary, Witness, which devoted each part to one of four conflict regions—Juarez, Libya, South Sudan and Rio de Janeiro—as covered by a team of photojournalists based in those regions.

[12] On March 28, 2013, the channel premiered the Alexandra Pelosi-directed Fall to Grace, about the infidelity scandal that led to the 2011 resignation of New Jersey governor Jim McGreevey and resulted in him coming out as gay.

The miniseries gained broader exposure after Durst was arrested on first-degree murder charges in relation to Berman's death on March 14, 2015 (one day prior to the docuseries's finale).

[20][21] The America Undercover banner would go on to spawn two regular sub-series: Real Sex (a late night magazine-formatted series of specials that ran from 1992 to 2009, featuring frank explorations on a variety of mainstream and non-mainstream sexual matters[7]) and Autopsy (a series of specials that aired between 1994 and 2008, in which forensic pathologist Dr. Michael Baden provides analysis on criminal, suspicious and health-related death cases).

[33][34][35] In 2023, HBO premiered Last Call: When a Serial Killer Stalked Queer New York directed by Anthony Caronna, and executive produced by Liz Garbus, Dan Cogan and Charlize Theron.

[44] That same year, HBO premiered the feature-length documentaries The Truth vs. Alex Jones,[45] MoviePass, MovieCrash,[46] Elizabeth Taylor: The Lost Tapes,[47] Faye,[48] Money Electric: The Bitcoin Mystery,[49] and Night is Not Eternal.