As of 2020, it had more than 300 skilled nursing and rehabilitation centers, assisted living facilities hospice and home health care offices, and over 45,000 employees.

Welltower announced a partnership with Integra Health shortly after which will take over control of all but 10 skilled nursing facilities from ProMedica.

In 1982, the company acquired nursing home operator Cenco, for $209 million; total facilities were 105, in 19 states.

In July 2007, the company agreed to a $4.9 billion buyout offer from the private equity firm Carlyle Group; it will no longer be a publicly traded corporation.

In 2010 HCR ManorCare entered into a sale-leaseback transaction whereby the company sold off 338 post-acute, skilled nursing and assisted living facilities for US$6.1 billion.

[6] In March 2018, HCR ManorCare Inc, filed for Chapter 11 protection with $7.1 billion of debt as part of a pre-arranged deal to transfer ownership to its landlord Quality Care Properties Inc.[7] Welltower Inc., in a $1.95 billion all-cash deal, acquired Quality Care Properties as a joint venture with ProMedica in April 2018.

ProMedica acquired the operations of what was then HCR ManorCare for about $1.35 billion in cash plus the assumption of net liabilities.