1HDM, 2BC4, 4FQX, 4GBX, 4I0P310914999ENSG00000242386ENSG00000242092ENSG00000241296ENSMUSG00000079547P28068P35737Q31094NM_002118NM_010387NP_002109NP_034517HLA class II histocompatibility antigen, DM beta chain is a protein that in humans is encoded by the HLA-DMB gene.

[5][6] HLA-DMB belongs to the HLA class II beta chain paralogues.

This class II molecule is a heterodimer consisting of an alpha (DMA) and a beta (DMB) chain, both anchored in the membrane.

Its role in tumor immunology is undefined but has been shown to positively correlated with increased T-cell infiltration and improved prognosis in ovarian cancer.

Differential immune processes mediated by HLA-DMB may contribute to the disparity in cancer outcome.