4I0P311115001ENSG00000206292ENSG00000232957ENSMUSG00000024334P06340n/aNM_002119NM_015851NM_008206NP_002110n/aHLA class II histocompatibility antigen, DO alpha chain is a protein that in humans is encoded by the HLA-DOA gene.

[5][6] HLA-DOA belongs to the HLA class II alpha chain paralogues.

The heterodimer, HLA-DO, is found in lysosomes in B cells and regulates HLA-DM-mediated peptide loading on MHC class II molecules.

In comparison with classical HLA class II molecules, this gene exhibits very little sequence variation, especially at the protein level.

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