In July 1958 the squadron participated in NASA’s abort recovery tests of the Mercury space capsule in the Salton Sea.

During July 1959 HMR(M)-462 worked with the United States Army in El Paso, Texas, to conduct the initial aerial transport tests of the Hawk missile system.

One year later, the squadron worked with Convair Astronautics Corporation in San Diego to help construct Atlas missile silos.

Also during 1960, HMR(M)-462 joined with the Federal Aviation Administration, Sikorsky Aircraft, the U.S. Army, New York Airways and British technical representatives of the Decca Corporation to establish Instrument Flight Procedures for helicopters.

Assigned to Marine Aircraft Group 36 at Phu Bai Combat Base, the squadron was tasked with supporting the 3rd Marine Division resupplying outlying Fire Support Bases (FSBs) and Helicopter Landing Zones (LZs), troop transport, medical evacuation, tactical aircraft recovery (TAR), Command and Control flights (C&C), and reconnaissance team insert/extracts.

However during mid-late 1969, HMH-462 was tasked with supporting the 1st Marine Division, in Quảng Nam and Quảng Tín Province; and the South Korean 2nd Marine Brigade on search and destroy operations in the vicinity of Go Noi Island and LZ-211, south of Da Nang, in Operation Victory Dragon.

The squadron participated in numerous named operations including: Meade River, Taylor Common, Dawson River, Dewey Canyon, Purple Martin, Maine Crag, Apache Snow, Cameron Falls, Herkimer Mountain, Utah Mesa (USMC/USA), Virginia Ridge, Georgia Tar, Arlington Canyon, Idaho Canyon, Ellis Ravine (USA), Massachusetts Bay (USA), Iroquois Grove (USA), Williams Glade (USMC/USA), Durham Peak, Pipestone Canyon and a series of ROK Marine operations, "Victory Dragon" On 20 October 1969 as part of Operation Keystone Cardinal, HMH-462 departed from Phu Bai to the USS New Orleans for transport to Okinawa to provide support to Marine forces in Japan.

[2] Shortly thereafter, the squadron was embarked upon the USS Hancock and sailed back towards Cambodia to participate in the rescue operation of the SS Mayaguez.

In December 1989, a squadron detachment was assigned to participate in coup contingency operations in the Republic of the Philippines as part of Marine Aircraft Group 90.

However the proposed reorganization plan was changed to deactivate HMH-463 at MCAS Kaneohe Bay after a detailed cost analysis provided by HQMC Aviation.