[1]: 55  The squadron had to address various technical teething problems including excessive rotor vibration and sand damage to the engines.

As a result of these collisions, two Marines were killed and seven injured and all three helicopters were too badly damaged for recovery and had to be destroyed.

[3]: 281  In late April the squadron supported The Hill Fights around Khe Sanh Combat Base.

In early November the squadron embarked on board Amphibious Ready Group Bravo, alternating maintenance and training at Subic Bay and periods at sea along the littoral of South Vietnam, from the Cà Mau Peninsula to the Vietnamese Demilitarized Zone.

[7]: 95–9  In late June the squadron again transported South Vietnamese forces in support of Operation Lam Son 72.

[7]: 110 Throughout 1974 and into early 1975 squadron units were always assigned as a component of the 31st MAU on board Amphibious Ready Group Alpha ships.

[8]: 200 With the advent of the Unit Deployment Program, on 1 September 1978, HMM-164 returned home to MCAS Santa Ana, California.

In June 1990, HMM-164 deployed to the Western Pacific with the 13th Marine Expeditionary Unit (13th MEU) and provided support relief efforts following the July earthquake that devastated the Philippines.

The squadron provided support to Joint Task Force (Somalia) during Operation Restore Hope from December 1992 until February 1993.

In August 1993, the Marine Corps Aviation Association chose HMM-164 as the Medium Helicopter Squadron of the year.

During this time it provided support for the United States Central Command in Operation Vigilant Sentinel in Kuwait as well as Bahrain, Qatar, and United Arab Emirates before returning and relocating to MCAS El Toro, California in December 1995.

In February 1996, HMM-164 was called upon to support the President of the United States as he visited the flood-ravaged areas around Portland, Oregon.

HMM-164 (REIN) returned to MCAS El Toro on February 26, 1998, completing its final deployment before re-designation as a Fleet Replacement Squadron.

During March 1999, the squadron deployed two aircraft to Moffett Federal Airfield to support Operation Urban Warrior and accept its first two student pilots.

On 28 June 2008, HMMT-164 deployed to Naval Air Station Lemoore after California Governor Arnold Schwarzenegger requested military assistance to fight raging wildfires.

The helicopters are providing medium lift rotary wing support to United States Northern Command and the National Fire Center.