Provide assault support transport of combat troops, supplies and equipment during expeditionary, joint or combined operations.

A four-plane detachment from HMH-463 deployed to Marble Mountain Air Facility in South Vietnam in January 1967 and was assigned to Marine Aircraft Group 16.

[3] On 8 January 1968, CH-53A #65-100 crashed in the Hải Lăng Forest south of Đông Hà Combat Base, killing all 46 personnel on board.

This entailed delivering an elephant via helicopter from the airstrip at Chu Lai Air Base to the Special Forces camp at Tra Bong to work at a local saw mill.

Once they encountered enemy contact they would then fly over the area again and drop 55 gallon drums of gasoline and napalm that were sling-loaded to the bottom of the aircraft.

On a mission over "Charlie Ridge" just west of Danang the squadron dropped over 400 tons of the fuel mixture against entrenched North Vietnamese Army positions.

The squadron remained in Southwest Asia to participate in Operation Desert Storm before returning to MCAF Kaneohe Bay in March 1991.

On 14 January 2016 twelve Hawaii Marines were killed when two CH-53E Super Stallion helicopters collided off of Oahu’s North Shore.