[3] The first significant voyage by Chatham was Vancouver's five-year mission to the South Seas and Pacific Northwest coast of America.

Among the other achievements of Chatham's crew was the exploration of the Columbia River as far as the Columbia River Gorge, reaching present-day eastern Multnomah County east of Portland and north west of Mount Hood.

A plaque erected by the State of Oregon along Interstate 84 commemorates the spot where Broughton landed in 1792.

In 1792, while near Fife Sound in Queen Charlotte Strait, the ship ran aground on rocks within a day, and about 2 miles (3.2 km) away, from where Discovery had done the same.

[3] In 2008, a scuba fisherman found a 900-pound (410 kg) anchor off Whidbey Island in Washington that he and others believe was lost from HMS Chatham on 9 June 1792.