HMS Grimsby was a Sandown-class minehunter of the British Royal Navy, serving from 1999–2022, and the second ship to bear the name.

Sandown-class MCMVs are highly manoeuvrable vessels due to being fitted with Voith-Schneider propulsors allowing rapid turning at slow speeds or whilst stationary.

Armament is primarily for self-defence against an asymmetric warfare threat although a point defence capability exists.

Grimsby was part of Mine Counter Measures Squadron 1[4] based at HMNB Clyde, Faslane, on the Gare Loch.

On 24 January 2002, while her divers were searching for a 500 lb (230 kg) bomb in Gibraltar, she was approached by the Spanish patrol boat Conejera, which refused to leave when asked by the crew of HMS Ranger, claiming they were in Spanish waters.